BAI1 anticorps (AA 670-750)

N° du produit ABIN7223780

Cet anticorps Lapin Polyclonal détecte spécifiquement BAI1 dans ELISA, WB, IHC (p) et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour BAI1 anticorps (AA 670-750) (ABIN7223780)

Antigène: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAI1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-BAI1 anticorps

Épitope: AA 670-750

Fonction: BAI-1 Polyclonal Antibody

Specificité: BAI-1 Polyclonal Antibody detects endogenous levels of BAI-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human BAI-1 at AA range: 670-750

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur BAI1

Antigène: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Autre désignation: BAI-1

Sujet: Rabbit Anti-BAI-1 Polyclonal Antibody,BAI1, Brain-specific angiogenesis inhibitor 1,Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 (adhesion G protein-coupled receptor B1, ADGRB1) contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.,Brain-specific angiogenesis inhibitor 1

ID gène: 575

UniProt: O14514

Pathways: Signalisation p53