BCAR1 anticorps (pTyr249)
Aperçu rapide pour BCAR1 anticorps (pTyr249) (ABIN7226022)
Antigène
Voir toutes BCAR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr249
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Fonction
- Rabbit Anti-p130 Cas (phospho Tyr249) Polyclonal Antibody
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Specificité
- Phospho-p130 Cas (Y249) Polyclonal Antibody detects endogenous levels of p130 Cas protein only when phosphorylated at Y249.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from human p130 Cas Phospho-Tyr249
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
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Autre désignation
- p130 Cas
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Sujet
- BCAR1, CAS, CASS1, CRKAS, Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, p130casBCAR1 (BCAR1, Cas family scaffolding protein), or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion.
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Poids moléculaire
- 130kD
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ID gène
- 9564
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UniProt
- P56945
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
Antigène
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