Cadherin 8 anticorps (AA 460-540)
Aperçu rapide pour Cadherin 8 anticorps (AA 460-540) (ABIN7218878)
Antigène
Voir toutes Cadherin 8 (CDH8) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 460-540
-
Fonction
- Cadherin-8 Polyclonal Antibody
-
Specificité
- Cadherin-8 Polyclonal Antibody detects endogenous levels of Cadherin-8 protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogène
- Synthesized peptide derived from the Internal region of human Cadherin-8 at AA range: 460-540
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
-
Commentaires
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- Cadherin 8 (CDH8)
-
Autre désignation
- Cadherin-8
-
Sujet
- Rabbit Anti-Cadherin-8 Polyclonal Antibody,CDH8, Cadherin-8,CDH8 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.,Cadherin-8
-
Poids moléculaire
- observerd band 90kDa
-
ID gène
- 1006
-
UniProt
- P55286
-
Pathways
- Cell-Cell Junction Organization
Antigène
-