CSNK1A1 anticorps (pTyr321)

N° du produit ABIN7219750

L’anticorps anti-CSNK1A1 Polyclonal Lapin est utilisé pour la détection de CSNK1A1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour CSNK1A1 anticorps (pTyr321) (ABIN7219750)

Antigène: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSNK1A1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CSNK1A1 anticorps

Épitope: pTyr321

Fonction: Casein Kinase Iα (phospho Tyr321) Polyclonal Antibody

Specificité: Phospho-Casein Kinase Iα (Y321) Polyclonal Antibody detects endogenous levels of Casein Kinase Iα protein only when phosphorylated at Y321.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Casein Kinase Ialpha Phospho-Tyr321

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CSNK1A1

Antigène: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Autre désignation: Casein Kinase Ialpha

Sujet: Rabbit Anti-Casein Kinase Iα (phospho Tyr321) Polyclonal Antibody,CSNK1A1, Casein kinase I isoform alpha, CKI-alpha, CK1,CSNK1A1 (Casein Kinase 1 Alpha 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Infectious disease. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CSNK1G2. asein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at Ser-45. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed: 11955436, PubMed: 1409656, PubMed: 18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed: 23902688). asein kinase I (CK1) is a monomeric serine-threonine protein kinase with 7 isoforms: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. CK1 is involved in many cellular processes including DNA repair, cell division, nuclear localization and membrane transport. Isoforms are also integral to development.,Casein kinase I isoform alpha

Poids moléculaire: observerd band 35kDa

ID gène: 1452

UniProt: P48729

Pathways: Signalisation WNT, Signalisation Hedgehog