CD44 anticorps (pSer706)

N° du produit ABIN7226040

L’anticorps Lapin Polyclonal anti-CD44 a été validé pour WB et ELISA. Il convient pour détecter CD44 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CD44 anticorps (pSer706) (ABIN7226040)

Antigène: CD44

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD44 anticorps

Épitope: pSer706

Fonction: CD44 (phospho Ser706) Polyclonal Antibody

Specificité: Phospho-CD44 (S706) Polyclonal Antibody detects endogenous levels of CD44 protein only when phosphorylated at S706.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human CD44 Phospho-Ser706

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: Rabbit Anti-CD44 (phospho Ser706) Polyclonal Antibody,CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycopr,The protein encoded by CD44 (CD44 Molecule (Indian blood group)) is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for CD44 undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.,CD44 antigen

Poids moléculaire: observerd band 90kDa

ID gène: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling