CNGA1 anticorps (AA 370-450)

N° du produit ABIN7219474

Cet anticorps anti-CNGA1 Polyclonal Lapin (ABIN7219474) détecte spécifiquement CNGA1 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour CNGA1 anticorps (AA 370-450) (ABIN7219474)

Antigène: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNGA1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-CNGA1 anticorps

Épitope: AA 370-450

Fonction: Rabbit Anti-CNG-1 Polyclonal Antibody

Specificité: CNG-1 Polyclonal Antibody detects endogenous levels of CNG-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human CNG-1 at AA range: 370-450

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CNGA1

Antigène: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Autre désignation: CNG-1

Sujet: CNGA1, CNCG, CNCG1, cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel 1, Cyclic nucleotide-gated channel alpha-1, CNG channel alpha-1, CNG-1, CNG1, Cyclic nucleotide-gated channel, photoreceptor, Rod photoreceptor cGThe cyclic nucleotide gated channel alpha 1 encoded by CNGA1 is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 80kD

ID gène: 1259

UniProt: P29973

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction, Asymmetric Protein Localization