CDK7 anticorps (pThr170)

N° du produit ABIN7218924

Cet anticorps anti-CDK7 Polyclonal Lapin (ABIN7218924) détecte spécifiquement CDK7 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CDK7 anticorps (pThr170) (ABIN7218924)

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CDK7 anticorps

Épitope: pThr170

Fonction: Cdk7 (phospho Thr170) Polyclonal Antibody

Specificité: Phospho-Cdk7 (T170) Polyclonal Antibody detects endogenous levels of Cdk7 protein only when phosphorylated at T170.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Cdk7 Phospho-Thr170

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CDK7

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Autre désignation: Cdk7

Sujet: Rabbit Anti-Cdk7 (phospho Thr170) Polyclonal Antibody,CDK7, CAK, CAK1, CDKN7, MO15, STK1, Cyclin-dependent kinase 7, 39 kDa protein kinase, p39 Mo15, CDK-activating kinase 1, Cell division protein kinase 7, Serine/threonine-protein kinase 1, TFIIH basal transcription factor complex kinase subunit,The cyclin dependent kinase 7 encoded by CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.,Cyclin-dependent kinase 7

Poids moléculaire: observerd band 40kDa

ID gène: 1022

UniProt: P50613

Pathways: Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase