EPH Receptor B2 anticorps (AA 960-1040)
Aperçu rapide pour EPH Receptor B2 anticorps (AA 960-1040) (ABIN7220306)
Antigène
Voir toutes EPH Receptor B2 (EPHB2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 960-1040
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Fonction
- EphB2 Polyclonal Antibody
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Specificité
- EphB2 Polyclonal Antibody detects endogenous levels of EphB2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the C-terminal region of human EphB2 at AA range: 960-1040
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- EPH Receptor B2 (EPHB2)
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Autre désignation
- EphB2
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Sujet
- Rabbit Anti-EphB2 Polyclonal Antibody,EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5, Ephrin type-B receptor 2, Developmentally-regulated Eph-related tyrosine kinase, ELK-related tyrosine kinase, EPH tyrosine kinase 3, EPH-like kinase 5, EK5, hEK5, Renal carcinoma antigen NY-REN-47,EPHB2 encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.,Ephrin type-B receptor 2
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Poids moléculaire
- observerd band 117kDa
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ID gène
- 2048
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UniProt
- P29323
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Pathways
- Signalisation RTK, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
Antigène
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