FANCM anticorps

N° du produit ABIN7228482

L’anticorps anti-FANCM Polyclonal Lapin est utilisé pour la détection de FANCM dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour FANCM anticorps (ABIN7228482)

Antigène: FANCM (Fanconi Anemia Complementation Group M (FANCM))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCM est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FANCM anticorps

Fonction: Rabbit Anti-FANCM Polyclonal Antibody

Specificité: The antibody detects endogenous levels of FANCM protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human FANCM protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FANCM

Antigène: FANCM (Fanconi Anemia Complementation Group M (FANCM))

Autre désignation: FANCM

Sujet: Fanconi anemia group M protein, Protein FACM, ATP-dependent RNA helicase FANCM Fanconi anemia-associated polypeptide of 250 kDa, FAAP250, Protein Hef orthologThe Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants. FANCM (Fanconi Anemia Complementation Group M) is a Protein Coding gene. Diseases associated with FANCM include Fanconi Anemia, Complementation Group A and Fancm-Related Fanconi Anemia. Among its related pathways are Fanconi anemia pathway and DNA Double-Strand Break Repair.

Poids moléculaire: 225kD

ID gène: 57697

UniProt: Q8IYD8

Pathways: Réparation de l'ADN