FOXO4 anticorps (acLys189)

N° du produit ABIN7228584

L’anticorps anti-FOXO4 Polyclonal Lapin est utilisé pour la détection de FOXO4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour FOXO4 anticorps (acLys189) (ABIN7228584)

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FOXO4 anticorps

Épitope: acLys189

Fonction: Rabbit Anti-FoxO4 (Acetyl Lys189) Polyclonal Antibody

Specificité: The antibody detects endogenous levels of FoxO4 when Acetyl occurs at Lys189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human FoxO4 (Acetyl Lys189) protein at AA range: 189

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FOXO4

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Autre désignation: FoxO4

Sujet: Forkhead box protein O4, Fork head domain transcription factor AFX1FOXO4 encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving FOXO4 on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for FOXO4. FOXO4 (Forkhead Box O4) is a Protein Coding gene. Diseases associated with FOXO4 include Balloon Cell Malignant Melanoma and Sarcomatoid Squamous Cell Skin Carcinoma. Among its related pathways are AGE/RAGE pathway and RET signaling.

Poids moléculaire: 55kD

ID gène: 4303

UniProt: P98177

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation