FZD7 anticorps (AA 20-100)

N° du produit ABIN7214956

L’anticorps anti-FZD7 Polyclonal Lapin est utilisé pour la détection de FZD7 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, FACS et IF.

Aperçu rapide pour FZD7 anticorps (AA 20-100) (ABIN7214956)

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD7 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-FZD7 anticorps

Épitope: AA 20-100

Fonction: Rabbit Anti-Frizzled-7 Polyclonal Antibody

Specificité: Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human Frizzled-7 at AA range: 20-100

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,Flow Cyt 1:50-200,IF/ICC1:100-500,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FZD7

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Autre désignation: Frizzled-7

Sujet: FZD7, Frizzled-7, Fz-7, hFz7, FzE3Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. Frizzled-7 contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Poids moléculaire: 64kD

ID gène: 8324

UniProt: O75084

Pathways: Signalisation WNT, Stem Cell Maintenance