FZD8 anticorps (AA 460-540)

N° du produit ABIN7225246

Cet anticorps anti-FZD8 Polyclonal Lapin (ABIN7225246) détecte spécifiquement FZD8 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FZD8 anticorps (AA 460-540) (ABIN7225246)

Antigène: FZD8 (Frizzled Family Receptor 8 (FZD8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-FZD8 anticorps

Épitope: AA 460-540

Fonction: Rabbit Anti-Frizzled-8 Polyclonal Antibody

Specificité: Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Frizzled-8 at AA range: 460-540

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FZD8

Antigène: FZD8 (Frizzled Family Receptor 8 (FZD8))

Autre désignation: Frizzled-8

Sujet: FZD8, Frizzled-8, Fz-8, hFz8This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Poids moléculaire: 70kD

ID gène: 8325

UniProt: Q9H461

Pathways: Signalisation WNT