GDF5 anticorps (Internal Region)

N° du produit ABIN7218140

Cet anticorps anti-GDF5 est un anticorps Lapin Polyclonal détectant GDF5 dans WB, ELISA et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour GDF5 anticorps (Internal Region) (ABIN7218140)

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GDF5 anticorps

Épitope: Internal Region

Fonction: GDF-5 Polyclonal Antibody

Specificité: GDF-5 Polyclonal Antibody detects endogenous levels of GDF-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human GDF-5

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur GDF5

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Autre désignation: GDF-5

Sujet: Rabbit Anti-GDF-5 Polyclonal Antibody,GDF5, CDMP1, Growth/differentiation factor 5, GDF-5, Cartilage-derived morphogenetic protein 1, CDMP-1, Radotermin,GDF5 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Growth/differentiation factor 5 regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.,Growth

Poids moléculaire: observerd band 55kDa

ID gène: 8200

UniProt: P43026