Growth Hormone Receptor anticorps (N-Term)

N° du produit ABIN7218650

L’anticorps Lapin Polyclonal anti-Growth Hormone Receptor a été validé pour WB et ELISA. Il convient pour détecter Growth Hormone Receptor dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Growth Hormone Receptor anticorps (N-Term) (ABIN7218650)

Antigène: Growth Hormone Receptor (GHR)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Growth Hormone Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Growth Hormone Receptor anticorps

Épitope: N-Term

Fonction: GHR Polyclonal Antibody

Specificité: GHR Polyclonal Antibody detects endogenous levels of GHR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human GHR

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Growth Hormone Receptor

Antigène: Growth Hormone Receptor (GHR)

Autre désignation: GHR

Sujet: Rabbit Anti-GHR Polyclonal Antibody,GHR, Growth hormone receptor, GH receptor, Somatotropin receptor,GHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.,Growth hormone receptor

Poids moléculaire: observerd band 70kDa

ID gène: 2690

UniProt: P10912

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Response to Growth Hormone Stimulus