HCK anticorps (pTyr521)

N° du produit ABIN7221456

Cet anticorps anti-HCK est un anticorps Lapin Polyclonal détectant HCK dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour HCK anticorps (pTyr521) (ABIN7221456)

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCK est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HCK anticorps

Épitope: pTyr521

Fonction: Hck (phospho Tyr521) Polyclonal Antibody

Specificité: Phospho-Hck (Y521) Polyclonal Antibody detects endogenous levels of Hck protein only when phosphorylated at Y521.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Hck Phospho-Tyr521

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur HCK

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Autre désignation: Hck

Sujet: Rabbit Anti-Hck (phospho Tyr521) Polyclonal Antibody,HCK, Tyrosine-protein kinase HCK, Hematopoietic cell kinase, Hemopoietic cell kinase, p59-HCK/p60-HCK, p59Hck, p61Hck,The HCK proto-oncogene, Src family tyrosine kinase encoded by HCK is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.,Tyrosine-protein kinase HCK

Poids moléculaire: observerd band 60kDa

ID gène: 3055

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling