HDAC1 anticorps (AA 410-490)
Aperçu rapide pour HDAC1 anticorps (AA 410-490) (ABIN7215242)
Antigène
Voir toutes HDAC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 410-490
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Fonction
- Histone deacetylase 1 Polyclonal Antibody
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Specificité
- Histone deacetylase 1 Polyclonal Antibody detects endogenous levels of Histone deacetylase 1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the C-terminal region of human Histone deacetylase 1 at AA range: 410-490
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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Autre désignation
- Histone deacetylase 1
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Sujet
- Rabbit Anti-Histone deacetylase 1 Polyclonal Antibody,HDAC1, RPD3L1, Histone deacetylase 1, HD1,Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone deacetylase 1 encoded by HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.,Histone deacetylase 1
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Poids moléculaire
- observerd band 55kDa
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ID gène
- 3065
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UniProt
- Q13547
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Pathways
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
Antigène
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