MLL4 anticorps (AA 1060-1140)

N° du produit ABIN7229698

L’anticorps Lapin Polyclonal anti-MLL4 a été validé pour IHC (p). Il convient pour détecter MLL4 dans des échantillons de Humain et Souris.

Aperçu rapide pour MLL4 anticorps (AA 1060-1140) (ABIN7229698)

Antigène: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLL4 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MLL4 anticorps

Épitope: AA 1060-1140

Fonction: MLL4 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MLL4 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human MLL4 protein at AA range: 1060-1140

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MLL4

Antigène: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Autre désignation: MLL4

Sujet: Rabbit Anti-MLL4 Polyclonal Antibody,Histone-lysine N-methyltransferase 2B , Lysine N-methyltransferase 2B, Myeloid/lymphoid or mixed-lineage leukemia protein 4, Trithorax homolog 2, WW domain-binding protein 7, WBP-7,KMT2B (Lysine Methyltransferase 2B) is a Protein Coding gene. Diseases associated with KMT2B include Dystonia 28, Childhood-Onset and Spindle Cell Sarcoma. Among its related pathways are Chromatin organization and Lysine degradation. KMT2B encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. KMT2B is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for KMT2B, however, the full length nature of the shorter transcript is not known.,MLL4

Poids moléculaire: observerd band 298kDa

ID gène: 9757

UniProt: Q9UMN6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, L'effet Warburg