Indian Hedgehog anticorps (Internal Region)
Aperçu rapide pour Indian Hedgehog anticorps (Internal Region) (ABIN7217598)
Antigène
Voir toutes Indian Hedgehog (IHH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Internal Region
-
Fonction
- Rabbit Anti-Ihh Polyclonal Antibody
-
Specificité
- Ihh Polyclonal Antibody detects endogenous levels of Ihh protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- Synthesized peptide derived from the Internal region of human Ihh
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
Date de péremption
- 12 months
-
-
- Indian Hedgehog (IHH)
-
Autre désignation
- Ihh
-
Sujet
- IHH, Indian hedgehog protein, IHH, HHG-2IHH encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. Indian hedgehog protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
-
Poids moléculaire
- 45kD
-
ID gène
- 3549
-
UniProt
- Q14623
-
Pathways
- Signalisation Hedgehog
Antigène
-