Integrin Alpha2b anticorps

N° du produit ABIN7211994

Cet anticorps Souris Monoclonal détecte spécifiquement Integrin Alpha2b dans IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Integrin Alpha2b anticorps (ABIN7211994)

Antigène: Integrin Alpha2b (CD41)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin Alpha2b est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Integrin Alpha2b anticorps

Fonction: Mouse Anti-CD41 Monoclonal Antibody

Specificité: The antibody detects endogenous human CD41/ Intergrin α2b protein.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogène: Synthetic Peptide

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: CD41

Sujet: ITGA2B, GP2B, ITGAB, Integrin alpha-IIb, GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb, CD41ITGA2B encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. Integrin subunit alpha 2b plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in ITGA2B are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.

ID gène: 3674

UniProt: P08514

Pathways: Integrin Complex