IL12RB2 anticorps (AA 270-350)

N° du produit ABIN7228994

Cet anticorps anti-IL12RB2 est un anticorps Lapin Polyclonal détectant IL12RB2 dans WB et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour IL12RB2 anticorps (AA 270-350) (ABIN7228994)

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12RB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL12RB2 anticorps

Épitope: AA 270-350

Fonction: I12R2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of I12R2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human I12R2 protein at AA range: 270-350

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur IL12RB2

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Autre désignation: I12R2

Sujet: Rabbit Anti-I12R2 Polyclonal Antibody,Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2,The Interleukin 12 Receptor Subunit Beta 2 encoded by IL12RB2 is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.,I12R2

Poids moléculaire: observerd band 94kDa

ID gène: 3595

UniProt: Q99665

Pathways: Signalistation JAK/STAT