IL13 Receptor alpha 1 anticorps (pTyr405)
Aperçu rapide pour IL13 Receptor alpha 1 anticorps (pTyr405) (ABIN7221804)
Antigène
Voir toutes IL13 Receptor alpha 1 (IL13RA1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr405
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Fonction
- IL-13Rα1 (phospho Tyr405) Polyclonal Antibody
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Specificité
- Phospho-IL-13Rα1 (Y405) Polyclonal Antibody detects endogenous levels of IL-13Rα1 protein only when phosphorylated at Y405.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human IL-13Ralpha1 Phospho-Tyr405
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
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Autre désignation
- IL-13Ralpha1
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Sujet
- Rabbit Anti-IL-13Rα1 (phospho Tyr405) Polyclonal Antibody,IL13RA1, IL13R, IL13RA, Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19, CD antigen CD213a1,The protein encoded by IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.,Interleukin-13 receptor subunit alpha-1
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Poids moléculaire
- observerd band 49kDa
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ID gène
- 3597
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UniProt
- P78552
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Pathways
- Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
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