CD25 anticorps
Aperçu rapide pour CD25 anticorps (ABIN7221754)
Antigène
Voir toutes CD25 (IL2RA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- IL-2Rα Polyclonal Antibody
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Specificité
- IL-2Rα Polyclonal Antibody detects endogenous levels of IL-2Rα protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human IL-2Ralpha around the non-phosphorylation site of S268
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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Autre désignation
- IL-2Ralpha
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Sujet
- Rabbit Anti-IL-2Rα Polyclonal Antibody,IL2RA, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD antigen CD25,The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.,Interleukin-2 receptor subunit alpha
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Poids moléculaire
- observerd band 55kDa
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ID gène
- 3559
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UniProt
- P01589
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Pathways
- Signalistation JAK/STAT, Growth Factor Binding, Activated T Cell Proliferation
Antigène
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