IL21 Receptor anticorps

N° du produit ABIN7229112

Cet anticorps Lapin Polyclonal détecte spécifiquement IL21 Receptor dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour IL21 Receptor anticorps (ABIN7229112)

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL21 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL21 Receptor anticorps

Fonction: IL21R Polyclonal Antibody

Specificité: The antibody detects endogenous levels of IL21R protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human IL21R protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur IL21 Receptor

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Autre désignation: IL21R

Sujet: Rabbit Anti-IL21R Polyclonal Antibody,Interleukin-21 receptor, IL-21 receptor, IL-21R, Novel interleukin receptor, CD_antigen: CD360,Interleukin 21 Receptor encoded by IL21R is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.,IL21R

Poids moléculaire: observerd band 59kDa

ID gène: 50615

UniProt: Q9HBE5

Pathways: Signalistation JAK/STAT