IRAK3 anticorps (AA 460-540)
Aperçu rapide pour IRAK3 anticorps (AA 460-540) (ABIN7219272)
Antigène
Voir toutes IRAK3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 460-540
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Fonction
- IRAK-M Polyclonal Antibody
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Specificité
- IRAK-M Polyclonal Antibody detects endogenous levels of IRAK-M protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the C-terminal region of human IRAK-M at AA range: 460-540
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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Autre désignation
- IRAK-M
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Sujet
- Rabbit Anti-IRAK-M Polyclonal Antibody,IRAK3, Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M,IRAK3 encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. Interleukin-1 receptor-associated kinase 3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.,Interleukin-1 receptor-associated kinase 3
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Poids moléculaire
- observerd band 68kDa
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ID gène
- 11213
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UniProt
- Q9Y616
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Antigène
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