KAT2B anticorps (AA 760-840)

N° du produit ABIN7216470

Cet anticorps Lapin Polyclonal détecte spécifiquement KAT2B dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KAT2B anticorps (AA 760-840) (ABIN7216470)

Antigène: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-KAT2B anticorps

Épitope: AA 760-840

Fonction: Rabbit Anti-PCAF Polyclonal Antibody

Specificité: PCAF Polyclonal Antibody detects endogenous levels of PCAF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human PCAF at AA range: 760-840

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur KAT2B

Antigène: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Autre désignation: PCAF

Sujet: KAT2B, PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Histone acetylase PCAF, Lysine acetyltransferase 2B, P300/CBP-associated factor, P/CAFCBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. Lysine acetyltransferase 2B encoded by KAT2B associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that lysine acetyltransferase 2B plays a direct role in transcriptional regulation.

Poids moléculaire: 93kD

ID gène: 8850

UniProt: Q92831

Pathways: Signalisation p53, Regulation of Carbohydrate Metabolic Process