LIG3 anticorps (AA 110-190)
Aperçu rapide pour LIG3 anticorps (AA 110-190) (ABIN7214588)
Antigène
Voir toutes LIG3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 110-190
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Fonction
- DNA Ligase III Polyclonal Antibody
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Specificité
- DNA Ligase III Polyclonal Antibody detects endogenous levels of DNA Ligase III protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human DNA Ligase III at AA range: 110-190
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
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Autre désignation
- DNA Ligase III
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Sujet
- Rabbit Anti-DNA Ligase III Polyclonal Antibody,LIG3, DNA ligase 3, DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3,LIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.,DNA ligase 3
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Poids moléculaire
- observerd band 100kDa
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ID gène
- 3980
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UniProt
- P49916
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Pathways
- Réparation de l'ADN
Antigène
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