MED13 anticorps (AA 650-730)

N° du produit ABIN7226192

Cet anticorps anti-MED13 Polyclonal Lapin (ABIN7226192) détecte spécifiquement MED13 dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MED13 anticorps (AA 650-730) (ABIN7226192)

Antigène: MED13 (Mediator Complex Subunit 13 (MED13))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED13 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MED13 anticorps

Épitope: AA 650-730

Fonction: Rabbit Anti-TRAP240 Polyclonal Antibody

Specificité: TRAP240 Polyclonal Antibody detects endogenous levels of TRAP240 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human TRAP240 at AA range: 650-730

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MED13

Antigène: MED13 (Mediator Complex Subunit 13 (MED13))

Autre désignation: TRAP240

Sujet: MED13, ARC250, KIAA0593, THRAP1, TRAP240, Mediator of RNA polymerase II transcription subunit 13, Activator-recruited cofactor 250 kDa component, ARC250, Mediator complex subunit 13, Thyroid hormone receptor-associated protein 1, Thyroid hoMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of MED13 is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.

ID gène: 9969

UniProt: Q9UHV7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha