MED13 anticorps (AA 61-240) (Biotin)

N° du produit ABIN8008539

L’anticorps anti-MED13 Polyclonal Lapin est utilisé pour la détection de MED13 dans des échantillons de Humain et Souris. Il a été validé pour ELISA, IHC et WB.

Aperçu rapide pour MED13 anticorps (AA 61-240) (Biotin) (ABIN8008539)

Antigène: MED13 (Mediator Complex Subunit 13 (MED13))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED13 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-MED13 anticorps (Biotin)

Épitope: AA 61-240

Fonction: Anti-MED13 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human MED13 recombinant protein (Position: L61-Y240).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MED13

Antigène: MED13 (Mediator Complex Subunit 13 (MED13))

Autre désignation: MED13

Sujet:

Background: Mediator complex subunit 13 is a protein that in humans is encoded by the MED13 gene. This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.

Gene Full Name: mediator complex subunit 13

ID gène: 9969

UniProt: Q9UHV7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha