MED13 anticorps

N° du produit ABIN7464200

Détail du produit anti-MED13 anticorps

Antigène: MED13 (Mediator Complex Subunit 13 (MED13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED13 est non-conjugé

Application: Western Blotting (WB)

Specificité: Knockdown/Knockout validation was supported by references (PMID:36220895)

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human MED13. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur MED13

Antigène: MED13 (Mediator Complex Subunit 13 (MED13))

Autre désignation: mediator complex subunit 13 (MED13 Produits)

Synonymes: anticorps ARC250, anticorps DRIP250, anticorps HSPC221, anticorps THRAP1, anticorps TRAP240, anticorps 1110067M05Rik, anticorps D030023K18, anticorps Thrap1, anticorps Trap240, anticorps med13, anticorps wu:fb66c06, anticorps wu:fc43h07, anticorps wu:fc43h08, anticorps zgc:153454, anticorps skuld-like, anticorps mediator complex subunit 13, anticorps mediator complex subunit 13b, anticorps MED13, anticorps Med13, anticorps med13b

Sujet: Mediator complex subunit 13 , ARC250 , DRIP250 , HSPC221 , THRAP1 , TRAP240,This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq]

Poids moléculaire: 239 kDa

ID gène: 9969

UniProt: Q9UHV7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha