MIA3 anticorps (AA 1110-1190)

N° du produit ABIN7229662

Cet anticorps Lapin Polyclonal détecte spécifiquement MIA3 dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MIA3 anticorps (AA 1110-1190) (ABIN7229662)

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIA3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-MIA3 anticorps

Épitope: AA 1110-1190

Fonction: MIA3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MIA3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human MIA3 protein at AA range: 1110-1190

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MIA3

Antigène: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Autre désignation: MIA3

Sujet: Rabbit Anti-MIA3 Polyclonal Antibody,Transport and Golgi organization protein 1 homolog, TANGO1, C219-reactive peptide, D320, Melanoma inhibitory activity protein 3,MIA3 (MIA Family Member 3, ER Export Factor) is a Protein Coding gene. Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum.,MIA3

Poids moléculaire: observerd band 209kDa

ID gène: 375056

UniProt: Q5JRA6