MAPKAP Kinase 5 anticorps

N° du produit ABIN7225538

L’anticorps anti-MAPKAP Kinase 5 Polyclonal Lapin est utilisé pour la détection de MAPKAP Kinase 5 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour MAPKAP Kinase 5 anticorps (ABIN7225538)

Antigène: MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP Kinase 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MAPKAP Kinase 5 anticorps

Fonction: Rabbit Anti-PRAK Polyclonal Antibody

Specificité: PRAK Polyclonal Antibody detects endogenous levels of PRAK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human PRAK around the non-phosphorylation site of T182

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MAPKAP Kinase 5

Antigène: MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))

Autre désignation: PRAK

Sujet: MAPKAPK5, PRAK, MAP kinase-activated protein kinase 5, MAPK-activated protein kinase 5, MAPKAP kinase 5, MAPKAP-K5, MAPKAPK-5, MK-5, MK5, p38-regulated/activated protein kinase, PRAKThe protein encoded by MAPKAPK5 (mitogen-activated protein kinase-activated protein kinase 5) is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of MAPKAPK5 encoding distinct isoforms have been reported.

Poids moléculaire: 60kD

ID gène: 8550

UniProt: Q8IW41

Pathways: Signalisation MAPK