Neuregulin 4 anticorps (AA 11-60)
Aperçu rapide pour Neuregulin 4 anticorps (AA 11-60) (ABIN7230132)
Antigène
Voir toutes Neuregulin 4 (NRG4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 11-60
-
Fonction
- Rabbit Anti-NRG4 Polyclonal Antibody
-
Specificité
- The antibody detects endogenous levels of NRG4 protein
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- Synthesized peptide derived from part region of human NRG4 protein at AA range: 11-60
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
Date de péremption
- 12 months
-
-
- Neuregulin 4 (NRG4)
-
Autre désignation
- NRG4
-
Sujet
- Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4NRG4 (Neuregulin 4) is a Protein Coding gene. Among its related pathways are RET signaling and Signaling by ERBB2. GO annotations related to this gene include receptor binding and growth factor activity. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).
-
Poids moléculaire
- 12kD
-
ID gène
- 145957
-
UniProt
- Q8WWG1
-
Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
-