NET1 anticorps (AA 230-310)

N° du produit ABIN7227362

Cet anticorps anti-NET1 Polyclonal Lapin (ABIN7227362) détecte spécifiquement NET1 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour NET1 anticorps (AA 230-310) (ABIN7227362)

Antigène: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NET1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-NET1 anticorps

Épitope: AA 230-310

Fonction: Rabbit Anti-ARHG8 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ARHG8 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ARHG8 protein at AA range: 230-310

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NET1

Antigène: NET1 (Neuroepithelial Cell Transforming 1 (NET1))

Autre désignation: ARHG8

Sujet: Neuroepithelial cell-transforming gene 1 protein, Proto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8NET1 (Neuroepithelial Cell Transforming 1) is a Protein Coding gene. Diseases associated with NET1 include Breast Cancer. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway. NET1 is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by NET1 interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of NET1 are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Poids moléculaire: 65kD

ID gène: 10276

UniProt: Q7Z628

Pathways: Neurotrophin Signaling Pathway