PAK4 anticorps

N° du produit ABIN7218956

Cet anticorps Lapin Polyclonal détecte spécifiquement PAK4 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PAK4 anticorps (ABIN7218956)

Antigène: PAK4 (P21-Activated Kinase 4 (PAK4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PAK4 anticorps

Fonction: PAK4/5/6 Polyclonal Antibody

Specificité: PAK4/5/6 Polyclonal Antibody detects endogenous levels of PAK4/5/6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human PAK4 around the non-phosphorylation site of S474

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PAK4

Antigène: PAK4 (P21-Activated Kinase 4 (PAK4))

Autre désignation: PAK4/5/6

Sujet: Rabbit Anti-PAK4/5/6 Polyclonal Antibody,PAK4, KIAA1142, Serine/threonine-protein kinase PAK 4, p21-activated kinase 4, PAK-4,PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK5 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,serine threonine-protein kinase PAK 4

Poids moléculaire: observerd band 80kDa

ID gène: 10298

UniProt: O96013

Pathways: Signalisation RTK