PDE10A anticorps (AA 40-120)
Aperçu rapide pour PDE10A anticorps (AA 40-120) (ABIN7219164)
Antigène
Voir toutes PDE10A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-120
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Fonction
- PDE10A Polyclonal Antibody
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Specificité
- PDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the N-terminal region of human PDE10A at AA range: 40-120
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PDE10A (phosphodiesterase 10A (PDE10A))
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Autre désignation
- PDE10A
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Sujet
- Rabbit Anti-PDE10A Polyclonal Antibody,PDE10A, cAMP and cAMP-inhibited cGMP 3', 5'-cyclic phosphodiesterase 10A,The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for PDE10A.,cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
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Poids moléculaire
- observerd band 75kDa
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ID gène
- 10846
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UniProt
- Q9Y233
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Pathways
- cAMP Metabolic Process
Antigène
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