PLAT anticorps (N-Term)

N° du produit ABIN7223170

L’anticorps Lapin Polyclonal anti-PLAT a été validé pour WB et ELISA. Il convient pour détecter PLAT dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PLAT anticorps (N-Term) (ABIN7223170)

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAT est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PLAT anticorps

Épitope: N-Term

Fonction: tPA Polyclonal Antibody

Specificité: TPA Polyclonal Antibody detects endogenous levels of tPA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human tPA

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PLAT

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Autre désignation: tPA

Sujet: Rabbit Anti-tPA Polyclonal Antibody,PLAT, Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA, Alteplase, Reteplase,PLAT (plasminogen activator, tissue type) encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of PLAT results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,Tissue-type plasminogen activator

Poids moléculaire: observerd band 63kDa

ID gène: 5327

UniProt: P00750

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome