PIAS2 anticorps (AA 10-90)

N° du produit ABIN7216556

L’anticorps Lapin Polyclonal anti-PIAS2 a été validé pour WB et ELISA. Il convient pour détecter PIAS2 dans des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour PIAS2 anticorps (AA 10-90) (ABIN7216556)

Antigène: PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PIAS2 anticorps

Épitope: AA 10-90

Fonction: PIASx Polyclonal Antibody

Specificité: PIASx Polyclonal Antibody detects endogenous levels of PIASx protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human PIASx at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PIAS2

Antigène: PIAS2 (Protein Inhibitor of Activated STAT, 2 (PIAS2))

Autre désignation: PIASx

Sujet: Rabbit Anti-PIASx Polyclonal Antibody,PIAS2, PIASX, E3 SUMO-protein ligase PIAS2, Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, Msx-interacting zinc finger protein, Miz1, PIAS-NY protein, Protein inhibitor of activated STAT x, Protein inhibitor,PIAS2 encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PIAS2. Isoforms of protein inhibitor of activated STAT 2 enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of PIAS2 is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.,E3 SUMO-protein ligase PIAS2

Poids moléculaire: observerd band 68kDa

ID gène: 9063

UniProt: O75928

Pathways: Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling