RAD51 Homolog B anticorps (AA 180-260)

N° du produit ABIN7223904

Cet anticorps anti-RAD51 Homolog B Polyclonal Lapin (ABIN7223904) détecte spécifiquement RAD51 Homolog B dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Singe.

Aperçu rapide pour RAD51 Homolog B anticorps (AA 180-260) (ABIN7223904)

Antigène: RAD51 Homolog B (Rad51B)

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 Homolog B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RAD51 Homolog B anticorps

Épitope: AA 180-260

Fonction: Rabbit Anti-Rad51B Polyclonal Antibody

Specificité: Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Rad51B at AA range: 180-260

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RAD51 Homolog B

Antigène: RAD51 Homolog B (Rad51B)

Autre désignation: Rad51B

Sujet: RAD51B, RAD51L1, REC2, DNA repair protein RAD51 homolog 2, R51H2, RAD51 homolog B, Rad51B, RAD51-like protein 1The protein encoded by RAD51B (RAD51 paralog B) is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of RAD51B was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

Poids moléculaire: 45kD

ID gène: 5890

UniProt: O15315

Pathways: Réparation de l'ADN