RAP1A anticorps

N° du produit ABIN7230934

Cet anticorps anti-RAP1A Polyclonal Lapin (ABIN7230934) détecte spécifiquement RAP1A dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RAP1A anticorps (ABIN7230934)

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RAP1A anticorps

Fonction: Rabbit Anti-RAP1A Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RAP1A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RAP1A protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RAP1A

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Autre désignation: RAP1A

Sujet: C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1RAP1A encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of RAP1A have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 20kD

ID gène: 5906

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor