rala anticorps (AA 170-250)
Aperçu rapide pour rala anticorps (AA 170-250) (ABIN7230952)
Antigène
Voir toutes rala AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 170-250
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Fonction
- RASL1 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RASL1 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human RASL1 protein at AA range: 170-250
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- rala (Ras-related Protein Ral-A (rala))
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Autre désignation
- RASL1
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Sujet
- Rabbit Anti-RASL1 Polyclonal Antibody,RasGAP-activating-like protein 1, RAS protein activator like 1, Ras GTPase-activating-like protein,The protein encoded by RASAL1 (RAS Protein Activator Like 1) is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.,RASL1
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Poids moléculaire
- observerd band 88kDa
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ID gène
- 8437
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UniProt
- O95294
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Pathways
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
Antigène
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