rala anticorps (AA 170-250)

N° du produit ABIN7230952

Cet anticorps Lapin Polyclonal détecte spécifiquement rala dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour rala anticorps (AA 170-250) (ABIN7230952)

Antigène: rala (Ras-related Protein Ral-A (rala))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp rala est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-rala anticorps

Épitope: AA 170-250

Fonction: Rabbit Anti-RASL1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RASL1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RASL1 protein at AA range: 170-250

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur rala

Antigène: rala (Ras-related Protein Ral-A (rala))

Autre désignation: RASL1

Sujet: RasGAP-activating-like protein 1, RAS protein activator like 1, Ras GTPase-activating-like proteinThe protein encoded by RASAL1 (RAS Protein Activator Like 1) is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

Poids moléculaire: 88kD

ID gène: 8437

UniProt: O95294

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome