ARHGDIA anticorps (pSer174)

N° du produit ABIN7222202

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGDIA dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ARHGDIA anticorps (pSer174) (ABIN7222202)

Antigène: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGDIA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ARHGDIA anticorps

Épitope: pSer174

Fonction: Rabbit Anti-Rho GDIα (phospho Ser174) Polyclonal Antibody

Specificité: Phospho-Rho GDIα (S174) Polyclonal Antibody detects endogenous levels of Rho GDIα protein only when phosphorylated at S174.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Rho GDIalpha Phospho-Ser174

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ARHGDIA

Antigène: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Autre désignation: Rho GDIalpha

Sujet: ARHGDIA, GDIA1, Rho GDP-dissociation inhibitor 1, Rho GDI 1, Rho-GDI alphaARHGDIA encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 23kD

ID gène: 396

UniProt: P52565

Pathways: Neurotrophin Signaling Pathway