RYK anticorps (AA 150-230)

N° du produit ABIN7231216

Cet anticorps anti-RYK Polyclonal Lapin (ABIN7231216) détecte spécifiquement RYK dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour RYK anticorps (AA 150-230) (ABIN7231216)

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RYK est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RYK anticorps

Épitope: AA 150-230

Fonction: Rabbit Anti-RYK Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RYK protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RYK protein at AA range: 150-230

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RYK

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Autre désignation: RYK

Sujet: Tyrosine-protein kinase RYKThe protein encoded by RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 66kD

ID gène: 6259

UniProt: P34925

Pathways: Signalisation RTK, Signalisation WNT, Regulation of Cell Size