SCO2 anticorps (AA 181-230)
Aperçu rapide pour SCO2 anticorps (AA 181-230) (ABIN7231290)
Antigène
Voir toutes SCO2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 181-230
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Fonction
- Rabbit Anti-SCO2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of SCO2 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human SCO2 protein at AA range: 181-230
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
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Autre désignation
- SCO2
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Sujet
- Protein SCO2 homolog, mitochondrialCytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors, SCO2 encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in SCO2 are associated with fatal infantile encephalocardiomyopathy and myopia 6.
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Poids moléculaire
- 29kD
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ID gène
- 9997
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UniProt
- O43819
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Pathways
- Transition Metal Ion Homeostasis, L'effet Warburg
Antigène
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