STAT4 anticorps
Aperçu rapide pour STAT4 anticorps (ABIN7217140)
Antigène
Voir toutes STAT4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Stat4 Polyclonal Antibody
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Specificité
- Stat4 Polyclonal Antibody detects endogenous levels of Stat4 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human Stat4 around the non-phosphorylation site of Y693
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IP (2-5 μg/mg lysate), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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Autre désignation
- Stat4
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Sujet
- Rabbit Anti-Stat4 Polyclonal Antibody,STAT4, Signal transducer and activator of transcription 4,Signal transducer and activator of transcription 4 encoded by STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.,Signal transducer and activator of transcription 4
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Poids moléculaire
- observerd band 85kDa
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ID gène
- 6775
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UniProt
- Q14765
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Pathways
- Signalistation JAK/STAT
Antigène
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