SPHK2 anticorps
Aperçu rapide pour SPHK2 anticorps (ABIN7223680)
Antigène
Voir toutes SPHK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SphK2 Polyclonal Antibody
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Specificité
- SphK2 Polyclonal Antibody detects endogenous levels of SphK2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human SphK2 around the non-phosphorylation site of T614
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SPHK2 (Sphingosine Kinase 2 (SPHK2))
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Autre désignation
- SphK2
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Sujet
- Rabbit Anti-SphK2 Polyclonal Antibody,SPHK2, Sphingosine kinase 2, SK 2, SPK 2,SPHK2 (sphingosine kinase 2) encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for SPHK2.,Sphingosine kinase 2
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Poids moléculaire
- observerd band 70kDa
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ID gène
- 56848
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UniProt
- Q9NRA0
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Pathways
- VEGF Signaling
Antigène
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