Stanniocalcin 2 anticorps (AA 170-250)

N° du produit ABIN7231560

Cet anticorps anti-Stanniocalcin 2 Polyclonal Lapin (ABIN7231560) détecte spécifiquement Stanniocalcin 2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Stanniocalcin 2 anticorps (AA 170-250) (ABIN7231560)

Antigène: Stanniocalcin 2 (STC2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stanniocalcin 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Stanniocalcin 2 anticorps

Épitope: AA 170-250

Fonction: Rabbit Anti-STC2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of STC2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human STC2 protein at AA range: 170-250

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Stanniocalcin 2

Antigène: Stanniocalcin 2 (STC2)

Autre désignation: STC2

Sujet: Stanniocalcin-related protein, STC-related protein, STCRPSTC2 encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of STC2 is induced by estrogen and altered in some breast cancers.

Poids moléculaire: 33kD

ID gène: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome