TAPBP anticorps
Aperçu rapide pour TAPBP anticorps (ABIN7231882)
Antigène
Voir toutes TAPBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- TPSN Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of TPSN protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human TPSN protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
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Autre désignation
- TPSN
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Sujet
- Rabbit Anti-TPSN Polyclonal Antibody,Tapasin, TPN, TPSN, NGS-17, TAP-associated protein, TAP-binding protein,TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. TAPBP lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.,TPSN
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Poids moléculaire
- observerd band 49kDa
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ID gène
- 6892
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UniProt
- O15533
Antigène
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