TARDBP anticorps (AA 41-90)
Aperçu rapide pour TARDBP anticorps (AA 41-90) (ABIN7231678)
Antigène
Voir toutes TARDBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 41-90
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Fonction
- TADBP Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of TADBP protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human TADBP protein at AA range: 41-90
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Autre désignation
- TADBP
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Sujet
- Rabbit Anti-TADBP Polyclonal Antibody,TAR DNA-binding protein 43, TDP-43,HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by TARDBP is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.,TADBP
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Poids moléculaire
- observerd band 45kDa
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ID gène
- 23435
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UniProt
- Q13148
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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