TRIP12 anticorps (AA 950-1030)

N° du produit ABIN7231912

Cet anticorps anti-TRIP12 Polyclonal Lapin (ABIN7231912) détecte spécifiquement TRIP12 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TRIP12 anticorps (AA 950-1030) (ABIN7231912)

Antigène: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIP12 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TRIP12 anticorps

Épitope: AA 950-1030

Fonction: Rabbit Anti-TRIPC Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TRIPC protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human TRIPC protein at AA range: 950-1030

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TRIP12

Antigène: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Autre désignation: TRIPC

Sujet: E3 ubiquitin-protein ligase TRIP12, E3 ubiquitin-protein ligase for Arf, ULF, HECT-type E3 ubiquitin transferase TRIP12, Thyroid receptor-interacting protein 12, TR-interacting protein 12, TRIP-12TRIP12 (Thyroid Hormone Receptor Interactor 12) is a Protein Coding gene. Diseases associated with TRIP12 include Non-Syndromic Intellectual Disability and Chronic Dacryocystitis. Among its related pathways are Class I MHC mediated antigen processing and presentation and Ubiquitin mediated proteolysis. The protein encoded by TRIP12 is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.

Poids moléculaire: 219kD

ID gène: 9320

UniProt: Q14669

Pathways: Nuclear Hormone Receptor Binding